Filling Machines / Pharma Filling Machines
Automatic Respules Filling And Ultrasonic Sealing Machine
Peristaltic 2–5 ml respule filler with ultrasonic sealing in single-head and five-head versions. Engineered by Technogen Enterprise, Ahmedabad, India.

Machine Overview
The Automatic Respules Filling and Ultrasonic Sealing Machine from Technogen Enterprise is designed for filling measured liquid doses into compatible plastic respules and closing them by ultrasonic sealing. The machine is relevant to pharmaceutical and healthcare packaging applications where a small, defined fill volume and a repeatable seal are required for single-use containers. Technogen Enterprise is an Ahmedabad-based manufacturer, supplier and exporter of respule filling and sealing machinery.
The technical information identifies two models: TGRFS-15, fitted with one peristaltic filling head, and TGRFS-50, fitted with five filling heads. Both are specified for 2–5 ml fill volumes, ±1% filling accuracy and LDPE/LLDPE respules. The listed production capacities are approximately 5–12 respules per minute and 45–50 respules per minute, respectively, with the product specification noting an operator-efficiency dependency. Ultrasonic sealing, PLC/HMI controls, clean dry compressed air and GMP-style stainless steel construction are included in the technical specification specifications.
Peristaltic pumping is useful where the metering flow path can be selected for the liquid and the disposable or cleanable tubing arrangement. The ultrasonic process closes the compatible plastic container using controlled acoustic energy and mechanical pressure. Buyers should provide a sample respule, material grade, neck geometry, liquid viscosity, dose accuracy needs and required hourly production. These details determine the appropriate filling head arrangement, handling system and sealing setup.
Applications
Operating Principle
The Respules Filling and Ultrasonic Sealing Machine combines liquid metering through a peristaltic pump with the closing of plastic respules by ultrasonic energy. The machine's sequence depends on the selected head count and container-handling arrangement, but the essential operations are container positioning, dose filling, sealing and discharge.
Respule Loading and Orientation
Compatible LDPE or LLDPE respules are presented to the filling positions using the arrangement specified for the selected model. Stable container presentation is necessary because the fill opening is small.
Peristaltic Dose Filling
The peristaltic pump delivers the set volume of liquid through its tubing path into the respule. The control system coordinates the metering cycle with container presence and the installed number of filling heads.
Transfer to Ultrasonic Sealing
Filled respules move to the sealing station, where the plastic neck or seal area is positioned between the relevant ultrasonic tooling.
Ultrasonic Closure
The sealing head applies ultrasonic energy and pressure to join the specified plastic surfaces. Operating settings must be qualified for the actual LDPE/LLDPE container geometry and material.
Discharge and Inspection
Sealed respules leave the machine for visual or integrity inspection and subsequent packing. The operator checks filling and seal quality according to the product's validated packaging procedure.
Process Selection Consideration
Sealing parameters must be developed for the actual respule polymer and neck geometry. Filling accuracy and seal quality are separate acceptance checks and should both be verified during product trials.
Salient Features
2–5 ml respule filling range on both technical models
TGRFS-15 single-head peristaltic filling configuration
TGRFS-50 five-head peristaltic filling configuration
Specified ±1% filling accuracy
Ultrasonic sealing system for compatible plastic respules
Designed for LDPE/LLDPE respules
PLC and HMI-based machine control
GMP-style SS 304 / SS 316L construction specified
Single-phase 230 V, 50 Hz power supply
6 bar clean dry air requirement
Model-specific output from 5–12 to 45–50 respules per minute
Specified sound level below 70 dB in the specified configuration table
Technical Specifications
Final specifications may vary with container size, product characteristics, selected model and approved configuration.
| Parameter | TGRFS-15 | TGRFS-50 |
|---|---|---|
| Filling Range | 2 – 5 ml | 2 – 5 ml |
| Filling Accuracy | ± 1% | ± 1% |
| Output (Approx.) | 5 – 12 respules/min depending upon human efficiency | 45 – 50 respules/min depending upon human efficiency |
| Number of Filling Heads | 1 (Single Head) | 5 |
| Pump Type | Peristaltic Pump | Peristaltic Pump |
| Sealing System | Ultrasonic Sealing | Ultrasonic Sealing |
| Respule Type | LDPE / LLDPE | LDPE / LLDPE |
| Power Supply | 230 V AC, 50 Hz, Single Phase | 230 V AC, 50 Hz, Single Phase |
| Air Supply | 6 bar Clean Dry Air | 6 bar Clean Dry Air |
| Control System | PLC + HMI | PLC + HMI |
| Construction | GMP Model, SS 304 / SS 316L | GMP Model, SS 304 / SS 316L |
| Machine Weight | Approx. 120 kg | Approx. 120 kg |
| Noise Level | < 70 dB | < 70 dB |
Applicable Industries
Frequently Asked Questions
Which respule sizes can the machine fill?
What is the difference between the two models?
Which filling technology is used?
How are the respules sealed?
What utilities are required?
Request Technical Quote
Discuss Automatic Respules Filling And Ultrasonic Sealing Machine with our engineering team.
Provide respule drawings, liquid properties, dose volume and production target for TGRFS machine selection.



